The CSF1 Polyclonal Antibody (CAB10854) is a valuable tool for researchers studying CSF1, a cytokine involved in the regulation of immune responses and development of macrophages. This antibody, generated in rabbits, exhibits high specificity and reactivity with human samples, making it suitable for use in various research applications such as Western blotting.CSF1, also known as macrophage colony-stimulating factor, plays a crucial role in the differentiation and function of macrophages, key players in the immune system's response to infection and inflammation. Dysregulation of CSF1 signaling has been implicated in diseases such as cancer, autoimmune disorders, and inflammatory diseases, making it an attractive target for therapeutic intervention.
By using the CSF1 Polyclonal Antibody, researchers can gain insights into the expression and function of CSF1 in different cell types and conditions, advancing our understanding of its role in immune regulation and disease pathogenesis. This antibody is a valuable tool for studies in immunology, oncology, and related fields, contributing to the development of novel therapeutic strategies targeting CSF1 signaling pathways.
Product Name:
CSF1 Rabbit Polyclonal Antibody
SKU:
CAB10854
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 33-190 of human CSF1 (NP_757351.1).
Cell membrane, Secreted, Single-pass type I membrane protein, extracellular space.
Calculated MW:
60kDa
Observed MW:
60kDa
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1435
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CSF1 Rabbit pAb (CAB10854) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
