The CSAD Polyclonal Antibody (CAB13845) is a vital tool for research involving CSAD, a key enzyme involved in the biosynthesis of the neurotransmitter, GABA. This antibody, produced in rabbits, is especially reactive with human samples and has been validated for use in Western blot applications. By binding specifically to CSAD protein, this antibody allows for precise detection and analysis in various cell types, making it an invaluable asset for studies in neuroscience and neurology.CSAD, also known as cysteine sulfinic acid decarboxylase, is a critical enzyme in the metabolism of sulfur-containing amino acids, playing a crucial role in the production of GABA, the primary inhibitory neurotransmitter in the central nervous system.
Research into CSAD is essential for understanding GABAergic neurotransmission and its implications for neurological disorders such as epilepsy, Parkinson's disease, and schizophrenia. By studying the function and regulation of CSAD, scientists can gain insights into potential therapeutic targets for these conditions.
Product Name:
CSAD Rabbit Polyclonal Antibody
SKU:
CAB13845
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 371-520 of human CSAD (NP_057073.4).
This gene encodes a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
51380
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CSAD Rabbit pAb (CAB13845) at 1:5000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
