Csad Antibody (PACO25969)
- SKU:
- PACO25969
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Csad Antibody (PACO25969)
The CSAD Antibody (PAC025969) is a polyclonal antibody designed for research involving CSAD, an enzyme involved in the biosynthesis of the amino acid cysteine. The antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications such as immunohistochemistry and ELISA. It binds specifically to the CSAD protein, enabling precise detection and analysis in different tissue types, making it ideal for studies in neurobiology and metabolic research.CSAD plays a crucial role in the regulation of cysteine levels in the body, which is essential for various physiological processes including the synthesis of glutathione, a key antioxidant.
Dysregulation of CSAD activity has been implicated in conditions such as neurodegenerative disorders, metabolic diseases, and oxidative stress-related conditions. Understanding the function of CSAD is essential for developing therapies that target cysteine metabolism for the treatment of these disorders.Overall, the CSAD Antibody (PAC025969) is a valuable tool for researchers interested in studying the role of CSAD in health and disease, providing insights into potential therapeutic strategies for a wide range of disorders.
| Antibody Name: | Csad Antibody (PACO25969) |
| Antibody SKU: | PACO25969 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Cysteine sulfinic acid, decarboxylase protein (1-493AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Csad antibody at 12µg/ml + NIH/3T3 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 56 kDa Observed band size: 56 kDa . |
| Background: | carboxy-lyase activity, L-cysteine catabolic process to taurine, taurine metabolic process |
| Synonyms: | Cysteine sulfinic acid, decarboxylase (EC 4.1.1.29) (Cysteine-sulfinate decarboxylase) (Sulfinoalanine decarboxylase), Csad |
| UniProt Protein Function: | CSAD: a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]Protein type: EC 4.1.1.29; Other Amino Acids Metabolism - taurine and hypotaurine; LyaseMolecular Function: carboxy-lyase activity; catalytic activity; lyase activity; pyridoxal phosphate binding; sulfinoalanine decarboxylase activityBiological Process: carboxylic acid metabolic process; L-cysteine catabolic process to taurine; taurine metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9DBE0 |
| NCBI GenInfo Identifier: | 21450351 |
| NCBI Gene ID: | 246277 |
| NCBI Accession: | NP_659191.1 |
| UniProt Secondary Accession: | Q9DBE0,Q8K566 |
| UniProt Related Accession: | Q9DBE0 |
| Molecular Weight: | 55,145 Da |
| NCBI Full Name: | cysteine sulfinic acid decarboxylase |
| NCBI Synonym Full Names: | cysteine sulfinic acid decarboxylase |
| NCBI Official Symbol: | Csad  |
| NCBI Official Synonym Symbols: | Csd  |
| NCBI Protein Information: | cysteine sulfinic acid decarboxylase |
| UniProt Protein Name: | Cysteine sulfinic acid decarboxylase |
| UniProt Synonym Protein Names: | Cysteine-sulfinate decarboxylase; Sulfinoalanine decarboxylase |
| Protein Family: | Cysteine sulfinic acid decarboxylase |
| UniProt Gene Name: | Csad  |
| UniProt Entry Name: | CSAD_MOUSE |
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