The CRTC3 Polyclonal Antibody (CAB15890) is a valuable tool for researchers studying CRTC3, a transcription factor involved in cellular processes such as metabolism, cell growth, and differentiation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blotting applications.CRTC3, also known as TORC3, plays a key role in regulating gene expression in response to various cellular signals, including stress and energy levels. Its involvement in diverse physiological processes makes it an important target for research in areas such as metabolic disorders, cancer, and neuronal function.
By utilizing the CRTC3 Polyclonal Antibody, researchers can detect and analyze CRTC3 protein levels in different cell types, enabling a better understanding of its functions and mechanisms of action. This antibody is a valuable tool for investigating the role of CRTC3 in various biological processes, leading to potential insights into therapeutic strategies for related diseases.
Product Name:
CRTC3 Rabbit Polyclonal Antibody
SKU:
CAB15890
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human CRTC3 (NP_073606.3).
This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Purification Method:
Affinity purification
Gene ID:
64784
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using CRTC3 Rabbit pAb (CAB15890) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
