The CRTC1 Polyclonal Antibody (CAB15412) is a valuable tool for researchers studying the CRTC1 protein, a transcriptional coactivator involved in cellular processes such as metabolism, cell growth, and inflammation. This antibody, produced in rabbits, is specifically reactive with human samples and has been validated for use in Western blot applications.CRTC1 plays a crucial role in regulating gene expression in response to various cellular signals, making it a key player in pathways related to energy balance, stress response, and metabolic diseases. By targeting CRTC1 with this antibody, researchers can effectively detect and analyze the protein in a variety of cell types, providing insights into its functions and potential therapeutic implications.
The importance of CRTC1 in cellular signaling and disease processes makes this antibody an essential tool for investigations in areas such as metabolism, cancer, and inflammation. By accurately monitoring CRTC1 expression and activity, researchers can uncover new mechanisms underlying these conditions and potentially identify novel targets for therapeutic interventions.
Product Name:
CRTC1 Rabbit Polyclonal Antibody
SKU:
CAB15412
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CRTC1 (NP_056136.2).
Enables cAMP response element binding protein binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol; nuclear body; and plasma membrane.
Purification Method:
Affinity purification
Gene ID:
23373
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using CRTC1 Rabbit pAb (CAB15412) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
