The CRTAC1 Polyclonal Antibody (CAB16541) is a powerful tool designed for researchers studying CRTAC1, a protein involved in bone formation and regeneration. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.CRTAC1, also known as cartilage acidic protein 1, is essential for maintaining healthy bone tissue and promoting bone growth. Research suggests that dysregulation of CRTAC1 may contribute to bone disorders and diseases such as osteoporosis.
By targeting and detecting CRTAC1 protein, this antibody enables detailed analysis of bone-related pathways and mechanisms, making it an invaluable resource for studies in bone biology and regenerative medicine.Understanding the role of CRTAC1 in bone metabolism and regeneration is crucial for developing new therapeutic strategies for bone-related conditions and injuries. By using the CRTAC1 Polyclonal Antibody, researchers can gain valuable insights into the function of CRTAC1 and its potential as a therapeutic target in the field of bone research.
Product Name:
CRTAC1 Rabbit Polyclonal Antibody
SKU:
CAB16541
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 312-661 of human CRTAC1 (NP_060528.3).
This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
55118
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse brain, using CRTAC1 Rabbit pAb (CAB16541) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
