Crotonyl-HIST1H2BC (K23) Antibody (PACO65141)
- SKU:
- PACO65141
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Applications:
- ELISA
- ICC
- Conjugation:
- Unconjugated
- Isotype:
- IgG
- Host Species:
- Rabbit
Description
Crotonyl-HIST1H2BC (K23) Antibody (PACO65141)
The Crotonyl-Hist1H2BC (K23) Antibody (PAC065141) is a powerful tool for researchers studying histone modifications and their impact on gene expression and cellular function. This antibody, produced through immunization of rabbits, specifically targets the crotonylated lysine 23 residue on the Hist1H2BC protein.Histone crotonylation is an emerging epigenetic modification that has been linked to the regulation of gene expression and chromatin structure. By targeting the crotonylated lysine 23 residue on Hist1H2BC, this antibody allows researchers to investigate the role of this specific histone modification in various biological processes.
Validated for use in applications such as Western blotting and immunoprecipitation, the Crotonyl-Hist1H2BC (K23) Antibody (PAC065141) is a valuable tool for studies in epigenetics, chromatin biology, and gene regulation. Its specificity and reactivity with human samples make it a reliable choice for researchers looking to explore the functional consequences of histone crotonylation in health and disease.
Product Name: | Crotonyl-HIST1H2BC (K23) Antibody |
Product Code: | PACO65141 |
Size: | 50µL |
Target Names: | HIST1H2BC |
Species Reactivity: | Human |
Host Species: | Rabbit |
Antigen Species: | Human |
Tested Applications: | ELISA, ICC; Recommended dilution: ICC:1:10-1:100 |
Isotype: | IgG |
Clone ID: | N/A |
Conjugate: | Non-conjugated |
Clonality: | Polyclonal |
Antigen: | Synthesized peptide derived from Human Histone H2B type 1-C/E/F/G/I protein (17-28aa) |
Form: | Liquid |
Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | Antigen Affinity Purified |
Storage: | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Aliases: | Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l), HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI, H2BFL, H2BFH, H2BFG, H2BFA, H2BFK |
Uniprot ID: | P62807 |
Background: | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Research Area: | Epigenetics and Nuclear Signaling |