The Cornulin Polyclonal Antibody (CAB8762) is a key tool for researchers studying Cornulin, a protein associated with epithelial differentiation and tissue remodeling processes. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to Cornulin, researchers can easily detect and analyze its presence in various cell types, making it an invaluable tool for studies in dermatology, wound healing, and cancer research.
Cornulin is a protein that plays a pivotal role in promoting tissue integrity and barrier function in epithelial cells. Its involvement in cell differentiation and pathways related to wound healing and carcinogenesis make it a valuable target for researchers investigating various skin disorders and cancer development. Understanding the functions and regulation of Cornulin is crucial for developing new therapeutic strategies aimed at enhancing tissue repair and preventing disease progression.
Product Name:
CRNN Rabbit Polyclonal Antibody
SKU:
CAB8762
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 396-495 of human CRNN (NP_057274.1).
This gene encodes a member of the "fused gene" family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. The encoded protein contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation.
Purification Method:
Affinity purification
Gene ID:
49860
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of HepG2 cells, using CRNN antibody (CAB8762) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
