The CRLS1 Polyclonal Antibody (CAB12388) is a valuable tool for researchers studying the CRLS1 protein, which is involved in important cellular processes related to lipid metabolism. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the CRLS1 protein, this antibody allows for the accurate detection and analysis of CRLS1 in various cell types, making it an ideal choice for studies in lipid metabolism, mitochondrial function, and related diseases.CRLS1, also known as cardiolipin synthase 1, plays a crucial role in the biosynthesis of cardiolipin, a unique phospholipid found in the inner mitochondrial membrane.
Cardiolipin is essential for mitochondrial function and has been linked to various diseases, including neurodegenerative disorders and metabolic diseases. Research into the function and regulation of CRLS1 can provide valuable insights into these conditions and potentially lead to the development of therapeutic interventions targeting lipid metabolism pathways.Overall, the CRLS1 Polyclonal Antibody (CAB12388) offers researchers a reliable tool for studying the role of CRLS1 in cellular processes and disease pathogenesis. Its specificity and sensitivity make it a valuable asset for studies aimed at unraveling the complex mechanisms underlying lipid metabolism and mitochondrial function.
Product Name:
CRLS1 Rabbit Polyclonal Antibody
SKU:
CAB12388
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human CRLS1 (NP_061968.1).
This gene encodes a member of the CDP-alcohol phosphatidyltransferase class-I family of proteins. The encoded enzyme catalyzes the synthesis of cardiolipin, a phospholipid component of mitochondrial membranes that is critical for mitochondrial function.
Purification Method:
Affinity purification
Gene ID:
54675
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of HL-60, using CRLS1 Rabbit pAb (CAB12388) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
