CRKL Rabbit Polyclonal Antibody (CAB0511)
- SKU:
- CAB0511
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CRKL Rabbit Polyclonal Antibody |
SKU: | CAB0511 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 201-300 of human CRKL (NP_005198.1). |
Sequence: | PEPA HAYA QPQT TTPL PAVS GSPG AAIT PLPS TQNG PVFA KAIQ KRVP CAYD KTAL ALEV GDIV KVTR MNIN GQWE GEVN GRKG LFPF THVK IFDP QNPD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CRKL |
Positive Sample: | MCF7,HeLa,Raji,Mouse brain,Mouse thymus,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, extrinsic component of postsynaptic membrane, neuromuscular junction, nucleoplasm |
Calculated MW: | 34kDa |
Observed MW: | 34kDa |
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
Purification Method: | Affinity purification |
Gene ID: | 1399 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |