The CRISP3 Polyclonal Antibody (PACO08603) is a valuable tool for researchers studying CRISP3, a protein involved in immune regulation and inflammation. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to CRISP3, this antibody allows for the detection and analysis of the protein in various cell types, making it a versatile tool for studies in immunology and cancer research.CRISP3, also known as cysteine-rich secretory protein 3, is involved in regulating immune responses and inflammation, making it a key player in diseases such as cancer and autoimmune disorders.
Understanding the role of CRISP3 in these conditions is essential for developing targeted therapies that could modulate immune function and potentially alleviate symptoms associated with these diseases.Overall, the CRISP3 Polyclonal Antibody (PACO08603) is a reliable reagent for researchers looking to study the role of CRISP3 in immune regulation and inflammation, with potential implications for the development of novel therapeutic strategies.
cysteine-rich secretory protein 3;CRISP3;Aeg2;CRISP-3;CRS3;MGC126588;SGP28;dJ442L6.3 ;
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the cysteine-rich secretory protein (CRISP) family within the CRISP, antigen 5 and pathogenesis-related 1 proteins superfamily. The encoded protein has an N-terminal CRISP, antigen 5 and pathogenesis-related 1 proteins domain, a hinge region, and a C-terminal ion channel regulator domain. This protein contains cysteine residues, located in both the N- and C-terminal domains, that form eight disulfide bonds, a distinguishing characteristic of this family. This gene is expressed in the male reproductive tract where it plays a role in sperm function and fertilization, and the female reproductive tract where it plays a role in endometrial receptivity for embryo implantation. This gene is upregulated in certain types of prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
