The CREM Polyclonal Antibody (CAB5624) is a vital tool for researchers studying Cellular Response Element Modulator (CREM), a transcription factor involved in immune system regulation and cellular response to various stimuli. This rabbit-raised antibody is specifically designed for binding to CREM proteins in human samples, making it an ideal choice for Western blot applications.CREM plays a crucial role in modulating gene expression in response to cellular stress, inflammation, and immune signaling pathways. By targeting CREM with this antibody, researchers can easily detect and analyze CREM levels in different cell types, providing valuable insights into the role of CREM in immune regulation and disease processes.
With its high reactivity and specificity, the CREM Polyclonal Antibody (CAB5624) is a valuable tool for studies in immunology, cancer research, and other fields where understanding the role of CREM is essential. By enabling the detection and analysis of CREM proteins, this antibody opens up new possibilities for investigating the mechanisms underlying immune response modulation and developing potential therapeutic strategies targeting CREM in disease contexts.
Product Name:
CREM Rabbit Polyclonal Antibody
SKU:
CAB5624
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CREM (NP_853549.1).
This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.
Purification Method:
Affinity purification
Gene ID:
1390
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CREM antibody (CAB5624) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
