The CREG1 (Cellular Repressor of E1A-stimulated Genes 1) Polyclonal Antibody (CAB16081) is a valuable tool for researchers studying the role of CREG1 in cellular processes. CREG1 is a nuclear and cytoplasmic protein involved in the regulation of cell growth, differentiation, and apoptosis, making it important in various biological pathways.This antibody, generated in rabbits, specifically targets CREG1 and has been validated for use in Western blot applications. Its high reactivity with human samples allows for accurate detection and analysis of CREG1 expression in different cell types, making it ideal for studies in cell biology, cancer research, and developmental biology.
Understanding the function of CREG1 is essential for unraveling its role in disease processes such as cancer progression, cardiovascular diseases, and neurodegenerative disorders. By utilizing this antibody, researchers can investigate the mechanisms by which CREG1 influences cellular functions and potentially develop targeted therapies for related conditions.
Product Name:
CREG1 Rabbit Polyclonal Antibody
SKU:
CAB16081
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 110-190 of human CREG1 (NP_003842.1).
The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.
Purification Method:
Affinity purification
Gene ID:
8804
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of K-562, using CREG1 antibody (CAB16081) at 1:700 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
