Description
CREG1 Monoclonal Antibody [PAT1C6AT] (CPAB0621)
The CREG1 Polyclonal Antibody (CPAB0621) is a valuable tool for researchers studying CREG1, a protein involved in cellular proliferation and differentiation. This antibody, generated in rabbits, demonstrates high specificity and sensitivity for detecting CREG1 in human samples, particularly in Western blot applications. By binding to the CREG1 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential component of studies in cell biology and cancer research.CREG1, also referred to as cellular repressor of E1A-stimulated genes 1, plays a crucial role in regulating cell growth and differentiation processes.
Its involvement in cellular function highlights its significance in cancer development, making it a promising target for therapeutic interventions in oncology. Research into the functions and mechanisms of CREG1 is essential for understanding its potential implications in cancer progression and for developing targeted therapies aimed at manipulating its activity for therapeutic benefit.
Product Name: | CREG1 Antibody |
Product Sku: | CPAB0621 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human CREG1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CREG1 protein 32-22 amino acids purified from Ecoli. |
Clone: | PAT1C6AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | CREG1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG1 |
Background: | Cellular Repressor of E1A-Stimulated Genes 1 (CREG1) both activates and inhibits gene expression to stimulate cellular proliferation and hinder differentiation. CREG1 antagonizes transcriptional activation and cellular transformation by E1A. CREG1 shares partial sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. CREG1 contributes to the transcriptional control of cell growth and differentiation. |
Synonyms: | Cellular repressor of E1A-stimulated genes 1, protein CREG1, CREG. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |