CREBBP Rabbit Polyclonal Antibody (CAB17096)
- SKU:
- CAB17096
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | CREBBP Rabbit Polyclonal Antibody |
SKU: | CAB17096 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-445 of mouse CREBBP (NP_001020603.1). |
Sequence: | MAEN LLDG PPNP KRAK LSSP GFSA NDNT DFGS LFDL ENDL PDEL IPNG ELSL LNSG NLVP DAAS KHKQ LSEL LRGG SGSS INPG IGNV SASS PVQQ GLGG QAQG QPNS TNMA SLGA MGKS PLNQ GDSS TPNL PKQA ASTS GPTP PASQ ALNP QAQK QVGL VTSS PATS QTGP GICM NANF NQTH PGLL NSNS GHSL MNQA QQGQ AQVM NGSL GAAG RGRG AGMP YPAP AMQG ATSS VLAE TLTQ VSPQ MAGH AGLN TAQA GGMT KMGM TGTT SPFG QPFS QTGG QQMG ATGV NPQL ASKQ SMVN SLPA FPTD IKNT SVTT VPNM SQLQ TSVG IVPT QAIA TGPT ADPE KRKL IQQQ LVLL LHAH KCQR REQA NGEV RACS LPHC RTMK NVLN HMTH CQAG KACQ VAHC ASSR QIIS HWKN CTRH DCPV CLPL KNAS DKRN QQTI L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CBP; KAT3A; CBP/p300; p300/CBP; CREBBP |
Positive Sample: | Mouse brain,Rat brain |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 172kDa |
Observed MW: | 290kDa |
Enables several functions, including DNA-binding transcription factor binding activity; TFIIB-class transcription factor binding activity; and disordered domain specific binding activity. Involved in several processes, including cellular response to virus; face morphogenesis; and negative regulation of interferon-beta production. Acts upstream of or within cellular response to hepatocyte growth factor stimulus; germ-line stem cell population maintenance; and regulation of gene expression. Located in chromatin and nucleus. Part of RNA polymerase II transcription regulator complex; histone acetyltransferase complex; and outer kinetochore. Is expressed in several structures, including alimentary system; embryo ectoderm; genitourinary system; heart; and skin. Used to study Rubinstein-Taybi syndrome; acute myeloid leukemia; autism spectrum disorder; and myelodysplastic syndrome. Human ortholog(s) of this gene implicated in Rubinstein-Taybi syndrome; acute lymphoblastic leukemia; and acute myeloid leukemia. Orthologous to human CREBBP (CREB binding protein).
Purification Method: | Affinity purification |
Gene ID: | 12914 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |