The CREB3L2 Polyclonal Antibody (CAB10554) is designed for research involving CREB3L2, a transcription factor involved in the regulation of genes related to cell growth, differentiation, and metabolism. The antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications such as immunohistochemistry and Western blotting. CREB3L2, also known as OASIS, plays a crucial role in cellular processes such as endoplasmic reticulum stress response and lipid metabolism. Its involvement in these pathways makes it a key player in diseases like diabetes, obesity, and neurodegenerative disorders.
The CREB3L2 Polyclonal Antibody enables the detection and analysis of CREB3L2 protein levels in different cell types, making it an essential tool for researchers studying these conditions.Understanding the function of CREB3L2 is pivotal for uncovering novel therapeutic targets and developing interventions for diseases characterized by dysregulation of cellular processes. The CREB3L2 Polyclonal Antibody provides researchers with a reliable tool to further investigate the role of CREB3L2 and its potential implications in various pathological conditions.
Product Name:
CREB3L2 Rabbit Polyclonal Antibody
SKU:
CAB10554
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-247 of human CREB3L2 (NP_001240704.1).
Endoplasmic reticulum membrane, Nucleus, Single-pass type II membrane protein.
Calculated MW:
57kDa
Observed MW:
60kDa
This gene encodes a member of the oasis bZIP transcription factor family. Members of this family can dimerize but form homodimers only. The encoded protein is a transcriptional activator. Translocations between this gene on chromosome 7 and the gene fused in sarcoma on chromosome 16 can be found in some tumors. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
64764
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CREB3L2 Rabbit pAb (CAB10554) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
