CREB3 Rabbit Polyclonal Antibody (CAB6567)
- SKU:
- CAB6567
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | CREB3 Rabbit Polyclonal Antibody |
SKU: | CAB6567 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human CREB3 (NP_006359.3). |
Sequence: | MELE LDAG DQDL LAFL LEES GDLG TAPD EAVR APLD WALP LSEV PSDW EVDD LLCS LLSP PASL NILS SSNP CLVH HDHT YSLP RETV SMDL ESES CRKE GTQM TPQH MEEL AEQE IARL VLTD EEKS LLEK EGLI LPET LPLT KTEE QILK RVRR KIRN KRSA QESR RKKK VYVG GLES RVLK YTAQ NMEL QNKV QLLE EQNL SLLD QLRK LQAM VIEI SNKT SSSS TC |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:10 - 1:100 |
Synonyms: | LZIP; LUMAN; sLZIP; CREB3 |
Positive Sample: | Jurkat,HeLa,293T,HepG2,Mouse brain,Mouse liver,Mouse pancreas |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endoplasmic reticulum membrane, Membrane, Nucleus, Single-pass type II membrane protein. |
Calculated MW: | 41kDa |
Observed MW: | 41kDa |
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 10488 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |