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CREB1 Polyclonal Antibody

SKU:
CAB21362
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
IHC
IF
$155 - $431
Frequently bought together:

Description

CREB1 Polyclonal Antibody (CAB21362)

The CREB1 Polyclonal Antibody (CAB10006) is a valuable tool for researchers studying CREB1, a transcription factor involved in various cellular processes including gene expression, cell differentiation, and neuronal plasticity. This antibody is produced by rabbits and is highly specific for detecting CREB1 in human samples, making it ideal for use in Western blot applications.CREB1, or cAMP response element-binding protein 1, plays a crucial role in regulating gene expression in response to cellular signals such as hormones, neurotransmitters, and growth factors. It is involved in diverse physiological processes, including learning and memory, circadian rhythms, and metabolism.

The ability to accurately detect and analyze CREB1 expression levels in different cell types makes this antibody a valuable tool for research in neuroscience, endocrinology, and cancer biology.Understanding the functions and regulatory mechanisms of CREB1 is essential for unraveling its role in various diseases, including neurological disorders, cancer, and metabolic disorders. The CREB1 Polyclonal Antibody provides researchers with a reliable means to study CREB1 expression and activity, facilitating further insights into its biological functions and potential therapeutic targets.

Product Name:CREB1 Polyclonal Antibody
Product Code:CAB21362
Reactivity:Human, Mouse, Rat
Applications:Immunohistochemistry, Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Mouse, Rat
Tested Applications:IHC-P, IF/ICC, ELISA
Key Applications:Immunohistochemistry, Immunofluorescence
Recommended Dilution:IHC-P 1:50-1:200, IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Cellular Location:Nucleus

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-341 of human CREB1 (NP_604391.1).
Sequence:MTMES GAENQ QSGDA AVTEA ENQQM TVQAQ PQIAT LAQVS MPAAH ATSSA PTVTL VQLPN GQTVQ VHGVI QAAQP SVIQS PQVQT VQSSC KDLKR LFSGT QISTI AESED SQESV DSVTD SQKRR EILSR RPSYR KILND LSSDA PGVPR IEEEK SEEET SAPAI TTVTV PTPIY QTSSG QYIAI TQGGA IQLAN NGTDG VQGLQ TLTMT NAAAT QPGTT ILQYA QTTDG QQILV PSNQV VVQAA SGDVQ TYQIR TAPTS TIAPG VVMAS SPALP TQPAE EAARK REVRL MKNRE AAREC RRKKK EYVKC LENRV AVLEN QNKTL IEELK ALKDL YCHKS D
Synonyms:CREB, CREB-1
Calculated MW:35kDa
Observed MW:Refer to figures

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