The CRD1 Antibody (PAC062087) is a valuable tool for researchers studying CD300A, an immune inhibitory receptor involved in regulating immune responses. This polyclonal antibody, produced in rabbits, is highly specific for human samples and is validated for use in Western blot applications. By targeting the CD300A protein, this antibody allows for the detection and analysis of CD300A expression in various cell types, making it well-suited for studies in immunology and cancer research.CD300A plays a crucial role in immune homeostasis by modulating inflammation and inhibiting allergic reactions.
Its involvement in immune response regulation makes it a promising target for investigations into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of CD300A is essential for developing therapeutic strategies that can leverage or regulate immune responses in these disease contexts.Overall, the CRD1 Antibody (PAC062087) offers researchers a reliable tool for studying CD300A and its role in immune regulation, with potential implications for the development of novel therapeutic approaches in various disease settings.
Antibody Name:
CRD1 Antibody (PACO62087)
Antibody SKU:
PACO62087
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:2000
Species Reactivity:
Arabidopsis thaliana
Immunogen:
Recombinant Arabidopsis thaliana Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, chloroplastic protein (37-409AA)
Western Blot. Positive WB detected in: Apium graveolens leaf tissue, Glycine max leaf tissue. All lanes: CRD1 antibody at 1:1000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 48 kDa. Observed band size: 48 kDa.
Background:
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
Synonyms:
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, chloroplastic (Mg-protoporphyrin IX monomethyl ester oxidative cyclase) (EC 1.14.13.81) (Copper response defect 1 protein) (Dicarboxylate diiron protein) (AtZIP) (MPE-cyclase), CRD1, ACSF AT103 CHL27 ZIP
UniProt Protein Function:
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
UniProt Protein Details:
NCBI Summary:
Encodes a putative ZIP protein with varying mRNA accumulation in leaves, stems and roots. Has a consensus carboxylate-bridged di-iron binding site.
