UniProt Protein Function: | CRB2: May play a role in polarized cells morphogenesis. Belongs to the Crumbs protein family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 9q33.3Cellular Component: protein complex; integral to membrane; plasma membrane; lipid raftMolecular Function: enzyme binding; aspartic-type endopeptidase inhibitor activity; calcium ion bindingBiological Process: somitogenesis; mesoderm formation; notochord formation; maintenance of epithelial cell polarity; positive regulation of BMP signaling pathwayDisease: Ventriculomegaly With Cystic Kidney Disease; Focal Segmental Glomerulosclerosis 9 |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q5IJ48 |
NCBI GenInfo Identifier: | 112420992 |
NCBI Gene ID: | 286204 |
NCBI Accession: | NP_775960.4 |
UniProt Secondary Accession: | Q5IJ48,Q0QD46, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6, A2A3N4 |
UniProt Related Accession: | Q5IJ48 |
Molecular Weight: | 134265 |
NCBI Full Name: | protein crumbs homolog 2 |
NCBI Synonym Full Names: | crumbs family member 2 |
NCBI Official Symbol: | CRB2Â Â |
NCBI Official Synonym Symbols: | FSGS9; VMCKDÂ Â |
NCBI Protein Information: | protein crumbs homolog 2 |
UniProt Protein Name: | Protein crumbs homolog 2 |
UniProt Synonym Protein Names: | Crumbs-like protein 2 |
Protein Family: | Protein crumbs |
UniProt Gene Name: | CRB2Â Â |
UniProt Entry Name: | CRUM2_HUMAN |