RAIDD/CRADD Rabbit Polyclonal Antibody (CAB1124)
- SKU:
- CAB1124
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | RAIDD/CRADD Rabbit Polyclonal Antibody |
SKU: | CAB1124 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human RAIDD/RAIDD/CRADD (NP_003796.1). |
Sequence: | MEAR DKQV LRSL RLEL GAEV LVEG LVLQ YLYQ EGIL TENH IQEI NAQT TGLR KTML LLDI LPSR GPKA FDTF LDSL QEFP WVRE KLKK AREE AMTD LPAG DRLT GIPS HILN SSPS DRQI NQLA QRLG PEWE PMVL SLGL SQTD IYRC KANH PHNV QSQV VEAF IRWR QRFG KQAT FQSL HNGL RAVE VDPS LLLH MLE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MRT34; RAIDD; RAIDD/CRADD |
Positive Sample: | HepG2,293T,K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 23kDa |
Observed MW: | 22kDa |
This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 8738 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |