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CRADD Monoclonal Antibody [PAT14G8AT] (CPAB0620)

SKU:
CPAB0620
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT14G8AT
Applications:
WB
ELISA
$179
Frequently bought together:

Description

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CRADD Monoclonal Antibody [PAT14G8AT] (CPAB0620)

The CRADD Polyclonal Antibody (CPAB0620) is specifically designed for research involving CRADD, a crucial protein involved in apoptotic signaling pathways. The antibody is produced in rabbits, ensuring high reactivity with human samples, and has been validated for use in Western blot applications. By binding to the CRADD protein, this antibody enables accurate detection and analysis in various cell types, making it an excellent tool for studies in cancer research and apoptosis regulation.CRADD, also known as CASP2 and RIP1 domain-containing protein 2, plays a vital role in cell death processes by facilitating the activation of caspases and modulating apoptosis.

Its involvement in apoptotic pathways makes it a key target for research into diseases like cancer, where dysregulation of cell death mechanisms is a common feature. Understanding the function of CRADD is essential for developing targeted therapies that aim to promote or inhibit apoptosis in cancer cells, offering new insights into potential treatment strategies.

Product Name:CRADD Antibody
Product Sku:CPAB0620
Size:5μg
Host Species:Mouse
Immunogen:Anti-human CRADD mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CRADD protein 1-199 amino acids purified from Ecoli.
Clone:PAT14G8AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:CRADD antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a
Background:CRADD is a 22kDa, widely-expressed cytosolic adaptor/signaling protein that induces cell apoptosis/cell death in numerous tissues. CRADD is a death domain (CARD) that recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes TNFR1A, RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.
Synonyms:RAIDD, MGC9163, CRADD, Death domain-containing protein CRADD, Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CASP2 and RIPK1 domain containing adaptor with death domain.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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