The CRACR2A Polyclonal Antibody (CAB13839) is a valuable tool for researchers studying CRACR2A, a protein involved in calcium release-activated calcium channel function. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the CRACR2A protein, this antibody enables precise detection and analysis in various cell types, making it an excellent choice for studies in cell biology and calcium signaling research.
CRACR2A is essential for regulating calcium influx in immune cells, playing a crucial role in immune response modulation and cell activation. Research into CRACR2A function is critical for understanding its impact on immune cell physiology and its potential contribution to diseases such as immune disorders and cancer. By investigating the role of CRACR2A, researchers can gain insights that may lead to the development of novel therapeutic approaches targeting calcium signaling pathways.
Product Name:
CRACR2A Rabbit Polyclonal Antibody
SKU:
CAB13839
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CRACR2A (NP_001138430.1).
Enables GTPase activity and calcium ion binding activity. Involved in several processes, including activation of store-operated calcium channel activity; positive regulation of JNK cascade; and store-operated calcium entry. Located in several cellular components, including Golgi apparatus; Weibel-Palade body; and immunological synapse.
Purification Method:
Affinity purification
Gene ID:
84766
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CRACR2A Rabbit pAb (CAB13839) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
