The CRACR2A Polyclonal Antibody (CAB13838) is a valuable tool for researchers studying CRACR2A, a protein involved in calcium release-activated calcium channel regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity in detecting CRACR2A in human samples, making it ideal for Western blot applications. By binding to CRACR2A, this antibody enables precise identification and analysis of CRACR2A expression in various cell types, facilitating studies in cellular signaling, calcium homeostasis, and immune responses.CRACR2A, also known as CRAC regulator 2A, is an essential component in calcium signaling pathways that play a crucial role in T cell activation and immune response regulation.
Dysregulation of CRACR2A has been implicated in various diseases, including autoimmune disorders and cancer. Therefore, understanding the function and expression of CRACR2A is vital for uncovering new therapeutic targets and developing strategies to modulate immune responses in disease settings.Overall, the CRACR2A Polyclonal Antibody (CAB13838) is a valuable tool for researchers aiming to investigate the role of CRACR2A in cellular signaling and immune modulation, paving the way for advancements in immunology, cancer research, and therapeutic development.
Product Name:
CRACR2A Rabbit Polyclonal Antibody
SKU:
CAB13838
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CRACR2A (NP_001138430.1).
Enables GTPase activity and calcium ion binding activity. Involved in several processes, including activation of store-operated calcium channel activity; positive regulation of JNK cascade; and store-operated calcium entry. Located in several cellular components, including Golgi apparatus; Weibel-Palade body; and immunological synapse.
Purification Method:
Affinity purification
Gene ID:
84766
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse liver, using CRACR2A Rabbit pAb (CAB13838) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
