The CRABP2 Polyclonal Antibody (CAB6119) is a powerful tool for researchers studying CRABP2, a protein involved in cellular retinoic acid binding. This antibody, generated in rabbits, exhibits high reactivity with human samples and is optimized for use in Western blot applications. By specifically binding to CRABP2, researchers can easily detect and analyze this protein in a variety of cell types, making it ideal for investigations in molecular biology, developmental biology, and cancer research.CRABP2 is known for its role in retinoid signaling pathways, playing a crucial role in the transport and regulation of retinoic acid within cells.
Dysregulation of CRABP2 has been linked to various diseases, including cancer and developmental disorders, making it an attractive target for therapeutic interventions. The CRABP2 Polyclonal Antibody enables scientists to explore the functions and mechanisms of CRABP2 in these contexts, providing valuable insights for the development of novel treatments and therapies.Overall, the CRABP2 Polyclonal Antibody offers researchers a reliable tool for investigating the biological and pathological roles of CRABP2, ultimately advancing our understanding of retinoic acid signaling and its implications for human health.
Product Name:
CRABP2 Rabbit Polyclonal Antibody
SKU:
CAB6119
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-94 of human CRABP2 (NP_001869.1).
Sequence:
VLGV NVML RKIA VAAA SKPA VEIK QEGD TFYI KTST TVRT TEIN FKVG EEFE EQTV DGRP CKSL VKWE SENK M
This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1382
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CRABP2 antibody (CAB6119) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 30s.
