CRABP2 Monoclonal Antibody [PAT2E11AT] (CPAB0539)
- SKU:
- CPAB0539
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- PAT2E11AT
- Applications:
- WB
- ELISA
Description
CRABP2 Monoclonal Antibody [PAT2E11AT] (CPAB0539)
The CRABP2 Polyclonal Antibody (CPAB0539) is a crucial tool for researchers studying CRABP2, a protein involved in cell growth and differentiation processes. This antibody, produced in rabbits, shows high specificity and reactivity towards human samples, making it a reliable choice for Western blot applications.CRABP2, also known as cellular retinoic acid-binding protein 2, plays a significant role in mediating the effects of retinoic acid, a key signaling molecule in cellular development and differentiation. By binding specifically to CRABP2, researchers can accurately detect and analyze the protein in a variety of cell types, facilitating studies in developmental biology, cancer research, and regenerative medicine.
The intricate functions of CRABP2 make it a compelling target for investigations into various diseases, including cancer and neurological disorders. By utilizing the CRABP2 Polyclonal Antibody, researchers can further explore the mechanisms underlying CRABP2's involvement in disease progression and potentially identify novel therapeutic targets for treatment strategies. Unlock the potential of CRABP2 research with this reliable and sensitive antibody.
Product Name: | CRABP2 Antibody |
Product Sku: | CPAB0539 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human CRABP2 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CRABP2 amino acids 1-138 purified from Ecoli. |
Clone: | PAT2E11AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | CRABP2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG2a |
Background: | CRABP2 NCBI Accession No: NP_001869 regulates the access of retinoic acid to the nuclear retinoic acid receptors. CRABP2 is involved in a regulatory feedback mechanism that controls the action of retinoic acid on cell differentiation. CRABP2 is involved in the conversion of vitamin A into its intracellular active form retinoic acid, which regulate the genes responsible for lipid metabolism and adipocyte differentiation. CRABP2 gene is located on chromosome 1q21-23 and this region has been linked with related disorders such as familial combined hyperlipidemia (FCHL) and type 2 diabetes mellitus. CRABP proteins are of low molecular weight having an important function in retinoic acid-mediated regulation of human skin growth and differentiation. |
Synonyms: | RBP6, CRABP-II, CRABP2, RETINOIC ACID-BINDING PROTEIN CELLULAR TYPE II, Cellular retinoic acid-binding protein 2, Cellular retinoic acid-binding protein II. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |