The CR2 Polyclonal Antibody (CAB8407) is a valuable tool for researchers studying the Complement Receptor 2 (CR2) protein, which plays a key role in the immune system's response to pathogens and infections. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.CR2 is a cell surface receptor involved in the activation of the complement system, a crucial part of the immune response that helps to clear pathogens from the body. By targeting the CR2 protein, researchers can gain insights into how the immune system recognizes and responds to threats, making this antibody essential for studies in immunology, infectious diseases, and autoimmune disorders.
With its ability to specifically detect and bind to CR2, the CAB8407 Polyclonal Antibody enables precise analysis of the protein in various cell types and tissues. This makes it an indispensable tool for investigating the role of CR2 in immune signaling pathways, inflammation, and immune system dysfunction. Researchers studying diseases such as lupus, rheumatoid arthritis, and other autoimmune conditions will find this antibody invaluable for advancing their understanding of disease mechanisms and potential therapeutic targets.
Product Name:
CR2 Rabbit Polyclonal Antibody
SKU:
CAB8407
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-590 of human CR2/CD21 (NP_001006659.1).
This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1380
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CR2/CD21 Rabbit pAb (CAB8407) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
