The CPT2 Rabbit Monoclonal Antibody is a valuable tool for researchers studying CPT2, a key enzyme involved in fatty acid metabolism and energy production in the mitochondria. This antibody, generated in rabbits, specifically targets the CPT2 protein and is highly reactive with human samples, making it ideal for Western blot applications.CPT2 plays a crucial role in the transportation of long-chain fatty acids into the mitochondria for beta-oxidation, a process essential for energy production during periods of fasting or prolonged exercise.
Dysregulation of CPT2 activity has been linked to metabolic disorders such as fatty acid oxidation disorders and metabolic myopathy.By accurately detecting and analyzing CPT2 levels in various cell types, this monoclonal antibody enables researchers to further explore the role of CPT2 in metabolic pathways and disorders. Understanding the function and regulation of CPT2 is important for developing targeted treatments for metabolic diseases and improving overall metabolic health.
Product Name:
CPT2 Rabbit Monoclonal Antibody
SKU:
CAB0653
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 559-658 of human CPT2 (P23786).
The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with carnitine palmitoyltransferase I, the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders.
Purification Method:
Affinity purification
Gene ID:
1376
Clone Number:
ARC0516
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CPT2 Rabbit mAb (CAB0653) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
