The CPT2 Polyclonal Antibody (CAB2876) is an essential tool for researchers studying Carnitine palmitoyltransferase 2 (CPT2), a key enzyme involved in fatty acid oxidation. This antibody, generated in rabbits, is highly specific to human CPT2 protein and is validated for use in Western blot applications. By binding to CPT2, researchers can accurately detect and analyze protein levels in a variety of cell types, making it an ideal choice for studies in metabolism, mitochondrial disorders, and muscle-related diseases.CPT2 plays a crucial role in the breakdown of long-chain fatty acids for energy production, making it a vital component of metabolism regulation.
Dysregulation of CPT2 activity has been associated with various metabolic disorders, including fatty acid oxidation disorders and muscle-related diseases. Understanding the function of CPT2 is essential for developing targeted therapies and interventions for these conditions.Overall, the CPT2 Polyclonal Antibody is a valuable tool for researchers seeking to explore the role of CPT2 in metabolism and disease pathogenesis. Its high specificity and sensitivity make it an excellent choice for Western blot analyses, paving the way for advancements in metabolic research and therapeutic development.
Product Name:
CPT2 Rabbit Polyclonal Antibody
SKU:
CAB2876
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 420-658 of human CPT2 (NP_000089.1).
The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with carnitine palmitoyltransferase I, the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders.
Purification Method:
Affinity purification
Gene ID:
1376
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat liver, using CPT2 Rabbit pAb (CAB2876) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.