CPT1A Rabbit Polyclonal Antibody (CAB5307)
- SKU:
- CAB5307
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | CPT1A Rabbit Polyclonal Antibody |
SKU: | CAB5307 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 520-720 of human CPT1A (NP_001867.2). |
Sequence: | WDIP GECQ EVIE TSLN TANL LAND VDFH SFPF VAFG KGII KKCR TSPD AFVQ LALQ LAHY KDMG KFCL TYEA SMTR LFRE GRTE TVRS CTTE SCDF VRAM VDPA QTVE QRLK LFKL ASEK HQHM YRLA MTGS GIDR HLFC LYVV SKYL AVES PFLK EVLS EPWR LSTS QTPQ QQVE LFDL ENNP EYVS SGGG FGPV ADDG Y |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CPT1; CPT1-L; L-CPT1; CPT1A |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion outer membrane, Multi-pass membrane protein. |
Calculated MW: | 88kDa |
Observed MW: | 88kDa |
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1374 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3. |