The CPSF6 Polyclonal Antibody (CAB5963) is a valuable tool for researchers studying CPSF6, a key protein involved in gene expression and RNA processing. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blotting applications. By binding to CPSF6, this antibody enables researchers to detect and analyze the protein in various cell types, making it ideal for studies in molecular biology and gene regulation.CPSF6, also known as Cleavage and Polyadenylation Specific Factor 6, plays a crucial role in mRNA processing and regulation of gene expression.
Dysregulation of CPSF6 has been implicated in diseases such as cancer, viral infections, and neurological disorders. Understanding the function and regulation of CPSF6 is essential for developing targeted therapies and diagnostic tools for these conditions.Overall, the CPSF6 Polyclonal Antibody is a reliable and sensitive tool for researchers investigating the role of CPSF6 in gene expression and disease pathology. Its high specificity and validation in Western blotting make it a valuable asset for laboratories conducting cutting-edge research in molecular biology and biomedicine.
Product Name:
CPSF6 Rabbit Polyclonal Antibody
SKU:
CAB5963
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human CPSF6 (NP_008938.2).
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.
Purification Method:
Affinity purification
Gene ID:
11052
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CPSF6 Rabbit pAb (CAB5963) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
