The CPSF2 Polyclonal Antibody (CAB9297) is a valuable tool for researchers studying the CPSF2 protein, which plays a crucial role in pre-mRNA processing and gene expression regulation. This antibody, produced in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot applications. By binding specifically to CPSF2, this antibody enables precise detection and analysis of the protein in a variety of cell types, making it an ideal choice for studies in molecular biology and gene regulation.CPSF2 is an essential component of the pre-mRNA 3' end processing machinery, contributing to the accurate cleavage and polyadenylation of mRNA transcripts.
Dysregulation of CPSF2 function has been linked to various diseases, including cancer and developmental disorders. Research into the mechanisms underlying CPSF2 activity is critical for understanding its role in gene expression and identifying potential therapeutic targets for diseases characterized by aberrant mRNA processing.Overall, the CPSF2 Polyclonal Antibody (CAB9297) offers researchers a reliable tool for investigating the function of CPSF2 in diverse biological processes, with implications for both basic science and clinical research.
Product Name:
CPSF2 Rabbit Polyclonal Antibody
SKU:
CAB9297
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 450-700 of human CPSF2 (NP_059133.1).
Predicted to enable RNA binding activity. Involved in mRNA 3'-end processing by stem-loop binding activity and cleavage. Located in membrane. Part of mRNA cleavage and polyadenylation specificity factor complex.
Purification Method:
Affinity purification
Gene ID:
53981
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CPSF2 Rabbit pAb (CAB9297) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
