The CPS1 Rabbit Monoclonal Antibody (CAB4214) is a powerful tool for researchers studying carbamoyl-phosphate synthetase 1 (CPS1), an enzyme involved in the urea cycle. This antibody, produced using rabbit monoclonal technology, is highly specific to CPS1 and is suitable for various applications such as Western blot, immunofluorescence, and immunohistochemistry.CPS1 plays a crucial role in the detoxification of ammonia in the body by converting it into urea. Dysregulation of CPS1 activity is associated with hyperammonemia, a condition characterized by elevated levels of ammonia in the blood.
By using the CPS1 Rabbit Monoclonal Antibody, researchers can investigate the expression levels and localization of CPS1 in different tissues and cell types, furthering our understanding of ammonia metabolism and related disorders.This antibody's high specificity and sensitivity make it an indispensable tool for studies focusing on urea cycle disorders, liver function, and metabolic diseases. With the CPS1 Rabbit Monoclonal Antibody, researchers can delve deeper into the molecular mechanisms underlying CPS1 function and its implications for human health.
Product Name:
CPS1 Rabbit Monoclonal Antibody
SKU:
CAB4214
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CPS1 (NP_001866.2).
The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.
Purification Method:
Affinity purification
Gene ID:
1373
Clone Number:
ARC0929
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using CPS1 Rabbit mAb (CAB4214) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
