CPS1 Rabbit Monoclonal Antibody (CAB4214)
- SKU:
- CAB4214
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | CPS1 Rabbit Monoclonal Antibody |
SKU: | CAB4214 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CPS1 (NP_001866.2). |
Sequence: | IIGN GGAP DTTA LDEL GLSK YLES NGIK VSGL LVLD YSKD YNHW LATK SLGQ WLQE EKVP AIYG VDTR MLTK IIRD KGTM LGKI EFEG QPVD FVDP NKQN L |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | PHN; GATD6; CPSASE1; CPS1 |
Positive Sample: | HeLa,Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion, Nucleus, nucleolus, Cell membrane |
Calculated MW: | 165kDa |
Observed MW: | 165kDa |
The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.
Purification Method: | Affinity purification |
Gene ID: | 1373 |
Clone Number: | ARC0929 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |