CPS1 Rabbit Polyclonal Antibody (CAB8080)
- SKU:
- CAB8080
- Product Type:
- Antibody
- Applications:
- WB
- IF
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | CPS1 Rabbit Polyclonal Antibody |
SKU: | CAB8080 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 750-970 of human CPS1 (NP_001866.2). |
Sequence: | IKNV VSGK TSAC FEPS LDYM VTKI PRWD LDRF HGTS SRIG SSMK SVGE VMAI GRTF EESF QKAL RMCH PSIE GFTP RLPM NKEW PSNL DLRK ELSE PSST RIYA IAKA IDDN MSLD EIEK LTYI DKWF LYKM RDIL NMEK TLKG LNSE SMTE ETLK RAKE IGFS DKQI SKCL GLTE AQTR ELRL KKNI HPWV KQID TLAA EYPS VTNY LYVT YNGQ EHDV N |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:50 - 1:200 |
Synonyms: | PHN; GATD6; CPSASE1; CPS1 |
Positive Sample: | HeLa,U2OS |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion, Nucleus, nucleolus. |
Calculated MW: | 165kDa |
Observed MW: | 165kDa |
The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.
Purification Method: | Affinity purification |
Gene ID: | 1373 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |