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CPOX Monoclonal Antibody [PAT36B10AT] (CPAB0235)

SKU:
CPAB0235
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT36B10AT
Applications:
WB
ELISA
FC
€149
Frequently bought together:

Description

system_update_alt Datasheet

CPOX Monoclonal Antibody [PAT36B10AT] (CPAB0235)

The CPOX Polyclonal Antibody (CPAB0235) is an essential tool for researchers studying the role of CPOX, an enzyme involved in heme biosynthesis, cellular metabolism, and oxidative stress response. This antibody, produced in rabbits, is highly specific for detecting CPOX in human samples and has been validated for use in Western blot applications.CPOX plays a critical role in maintaining cellular homeostasis by regulating the balance of heme production within cells. Dysregulation of this enzyme can lead to disorders such as porphyrias and other metabolic conditions.

By using the CPOX Polyclonal Antibody, researchers can accurately measure CPOX levels in various cell types and tissues, providing valuable insights into heme biosynthesis and its implications in diseases related to oxidative stress and metabolism.The versatility of this antibody makes it an ideal choice for studies in biochemistry, cell biology, and molecular biology. Its high specificity and sensitivity ensure reliable and reproducible results, making it a valuable tool for researchers in the fields of metabolic disorders, oxidative stress, and heme biology.

Product Name:CPOX Antibody
Product Sku:CPAB0235
Size:5μg
Host Species:Mouse
Immunogen:Anti-human CPOX mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CPOX amino acids 111-454 purified from Ecoli.
Clone:PAT36B10AT.
Reactivity:Human
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:CPOX antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1
Background:Coproporphyrinogen Oxidase (CPOX) which is localized to the internal membrane space of erythrocytes takes part in the 6th phase of heme biosynthesis. CPOX catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III. Mutations in human CPOX gene forecast the clinical result of the disease, with either hepatic hereditary coproporphyria or hematological manifestations of erythropoietic harderoporphyria.
Synonyms:CPO, CPX, HCP, Coproporphyrinogen-III oxidase, mitochondrial, COX, Coprogen oxidase, Coproporphyrinogenase, CPOX.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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