The CPNE4 Polyclonal Antibody (PAC039534) is a valuable tool for researchers studying CPNE4, a calcium-dependent membrane-binding protein involved in cell signaling and membrane trafficking. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for Western blot applications. By targeting the CPNE4 protein, researchers can accurately detect and analyze its expression in various cell types, providing insights into its role in cellular processes.CPNE4 is known for its diverse functions in cell biology, including regulating intracellular calcium levels and facilitating membrane fusion events. Its involvement in cell signaling pathways and membrane dynamics positions it as a potential target for investigating cellular processes related to neurotransmission, cell growth, and membrane trafficking.
By studying CPNE4, researchers can uncover its implications in various physiological and pathological conditions, offering potential avenues for therapeutic development.The CPNE4 Polyclonal Antibody is a valuable tool for researchers interested in exploring the functions and mechanisms of CPNE4 in cellular processes. Its high reactivity and specificity make it a reliable choice for studying CPNE4 expression in different experimental settings, providing crucial insights into the protein's role in cell biology and potential therapeutic applications.
Western Blot. Positive WB detected in: Rat brain tissue, Mouse brain tissue. All lanes: CPNE4 antibody at 2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 63, 65 kDa. Observed band size: 63 kDa.
Immunohistochemistry analysis of human brain tissue using PACO39534 at dilution of 1:100.
Immunohistochemistry analysis of human prostate tissue using PACO39534 at dilution of 1:100.
Background:
Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes.
Synonyms:
Copine-4 (Copine IV) (Copine-8), CPNE4
UniProt Protein Function:
CPNE4: May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties. Belongs to the copine family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 3q22.1
UniProt Protein Details:
NCBI Summary:
This gene belongs to the highly conserved copine family. It encodes a calcium-dependent, phospholipid-binding protein, which may be involved in membrane trafficking, mitogenesis and development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]