The CPNE1 Polyclonal Antibody (CAB15749) is a valuable tool for research involving CPNE1, a calcium-dependent phospholipid-binding protein implicated in various cellular processes. This antibody, generated in rabbits, is highly reactive with human samples and has been validated for use in applications such as Western blot and immunohistochemistry.CPNE1 is known to play a role in cell signaling, membrane trafficking, and membrane fusion events, making it a key player in processes such as exocytosis and endocytosis. Its involvement in these essential cellular functions makes CPNE1 a target of interest in studies related to cancer, neurodegenerative diseases, and cardiovascular disorders.
By utilizing the CPNE1 Polyclonal Antibody, researchers can detect and analyze the expression of CPNE1 protein in various cell types and tissues, allowing for a better understanding of its function and potential implications in disease pathology. This antibody is a valuable tool for researchers looking to further explore the role of CPNE1 in cellular processes and its potential as a therapeutic target.
Product Name:
CPNE1 Rabbit Polyclonal Antibody
SKU:
CAB15749
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 120-220 of human CPNE1 (NP_003906.2).
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. This gene and the gene for RNA binding motif protein 12 overlap at map location 20q11.21. Alternate splicing results in multiple transcript variants encoding different proteins.
Purification Method:
Affinity purification
Gene ID:
8904
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CPNE1 Rabbit pAb (CAB15749) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
