The CPN2 Polyclonal Antibody (PACO22241) is a valuable tool for researchers studying CPN2, a key enzyme involved in protein metabolism and folding. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting CPN2 in human samples, making it ideal for Western blot applications. By targeting the CPN2 protein, this antibody enables accurate analysis and visualization of CPN2 expression in a variety of cell types, providing valuable insights for research in biochemistry, cell biology, and disease mechanisms.CPN2, also known as carboxypeptidase N, plays a crucial role in protein processing and peptide maturation, making it a potential therapeutic target for conditions related to protein misfolding and aggregation.
By studying the function and regulation of CPN2, researchers can gain a better understanding of its involvement in diseases such as neurodegenerative disorders, metabolic syndromes, and cancer. The CPN2 Polyclonal Antibody offers a valuable tool for exploring the role of CPN2 in cellular processes and disease pathways, aiding in the development of targeted therapies and diagnostic tools.
Antibody Name:
CPN2 Antibody (PACO22241)
Antibody SKU:
PACO22241
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from C-terminal of human CPN2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HeLa cells, using CPN2 antibody.
Background:
The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit.
Synonyms:
ACBP; arginine carboxypeptidase (carboxypeptidase N); Carboxypeptidase N 83 kDa chain; Carboxypeptidase N large subunit; Carboxypeptidase N polypeptide 2
UniProt Protein Function:
CPN2: The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 3q29