The CPEB1 Polyclonal Antibody (CAB5913) is designed for research involving CPEB1, a protein implicated in the regulation of gene expression and translation. The antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications such as Western blot and immunohistochemistry. It specifically binds to the CPEB1 protein, allowing for accurate detection and analysis in different cellular environments.CPEB1, also known as cytoplasmic polyadenylation element-binding protein 1, plays a crucial role in controlling mRNA translation and stability, making it a key player in processes like cell division, development, and synaptic plasticity.
Dysregulation of CPEB1 has been associated with various diseases, including cancer and neurological disorders, highlighting its importance in cellular function and disease pathogenesis.Studying the function and regulation of CPEB1 can provide valuable insights into gene expression mechanisms and potential therapeutic targets in diseases influenced by altered mRNA translation. The CPEB1 Polyclonal Antibody is a valuable tool for researchers exploring the role of CPEB1 in health and disease.
Product Name:
CPEB1 Rabbit Polyclonal Antibody
SKU:
CAB5913
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 282-561 of human CPEB1 (NP_085097.3).
This gene encodes a member of the cytoplasmic polyadenylation element binding protein family. This highly conserved protein binds to a specific RNA sequence, called the cytoplasmic polyadenylation element, found in the 3' untranslated region of some mRNAs. The encoded protein functions in both the cytoplasm and the nucleus. It is involved in the regulation of mRNA translation, as well as processing of the 3' untranslated region, and may play a role in cell proliferation and tumorigenesis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
64506
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CPEB1 antibody (CAB5913) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
