The Carboxypeptidase B Polyclonal Antibody (CAB10486) is a valuable tool for researchers studying carboxypeptidase B, an enzyme involved in the breakdown of proteins. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to carboxypeptidase B, this antibody enables the detection and analysis of the enzyme in various cell types, making it ideal for studies in enzymology, protein degradation pathways, and biomedical research.Carboxypeptidase B is known for its role in peptide cleavage and protein digestion, making it a key player in processes such as food digestion and protein turnover within cells.
Understanding the function and regulation of this enzyme is crucial for unraveling its involvement in metabolic disorders, digestive diseases, and other conditions related to protein metabolism. The use of the Carboxypeptidase B Polyclonal Antibody opens up opportunities to explore the biological roles of this enzyme and its potential as a therapeutic target in various pathologies.
Product Name:
CPB1 Rabbit Polyclonal Antibody
SKU:
CAB10486
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 111-417 of human CPB1 (NP_001862.2).
Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma.
Purification Method:
Affinity purification
Gene ID:
1360
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CPB1 antibody (CAB10486) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
