The CPA6 Polyclonal Antibody (CAB13644) is a valuable tool for researchers studying CPA6, a member of the carboxypeptidase family known for its role in peptide metabolism. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By binding to the CPA6 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in metabolism, enzymology, and neuroscience research.CPA6 is a key enzyme involved in the breakdown of peptides, playing a crucial role in processes such as digestion and neurotransmitter regulation.
Its dysregulation has been associated with various disorders, including metabolic diseases, neurological conditions, and cancer. By investigating the function of CPA6, researchers can gain insights into these diseases and potentially identify new therapeutic targets for intervention.Overall, the CPA6 Polyclonal Antibody offers researchers a reliable tool for studying the function and regulation of CPA6 in various biological contexts, paving the way for advancements in understanding peptide metabolism and its implications in health and disease.
Product Name:
CPA6 Rabbit Polyclonal Antibody
SKU:
CAB13644
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 130-437 of human CPA6 (NP_065094.3).
The gene encodes a member of the peptidase M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature enzyme, which catalyzes the release of large hydrophobic C-terminal amino acids. This enzyme has functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Mutations in this gene may be linked to epilepsy and febrile seizures, and a translocation t(6;8)(q26;q13) involving this gene has been associated with Duane retraction syndrome.
Purification Method:
Affinity purification
Gene ID:
57094
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CPA6 Rabbit pAb (CAB13644) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
