The Cox7a1 Polyclonal Antibody (CAB14721) is a valuable tool for researchers studying Cox7a1, a critical protein involved in mitochondrial function and energy metabolism. This antibody, produced in rabbits, exhibits high reactivity with samples from various species, making it suitable for a wide range of research applications.Cox7a1 is a subunit of cytochrome c oxidase, an essential enzyme in the electron transport chain responsible for ATP production in the mitochondria. Dysregulation of Cox7a1 expression has been linked to mitochondrial dysfunction and energy metabolism disorders, making it a key target for studies in metabolic diseases, neurodegenerative disorders, and aging-related research.
By specifically binding to Cox7a1, this antibody enables precise detection and analysis of the protein in different cell types and tissues, allowing researchers to investigate its functions in physiological and pathological conditions. With its validated performance in Western blot applications, the Cox7a1 Polyclonal Antibody (CAB14721) is a reliable tool for advancing our understanding of mitochondrial biology and developing potential therapeutic strategies for related disorders.
Product Name:
COX7A1 Rabbit Polyclonal Antibody
SKU:
CAB14721
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-79 of human COX7A1 (NP_001855.1).
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (muscle isoform) of subunit VIIa and the polypeptide 1 is present only in muscle tissues. Other polypeptides of subunit VIIa are present in both muscle and nonmuscle tissues, and are encoded by different genes.
Purification Method:
Affinity purification
Gene ID:
1346
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse heart, using COX7A1 Rabbit pAb (CAB14721) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
