The COX5B Polyclonal Antibody (CAB2640) is a valuable tool for researchers studying the role of COX5B in mitochondrial function and cellular respiration. COX5B is a subunit of cytochrome c oxidase, the final enzyme complex in the mitochondrial electron transport chain. This antibody, raised in rabbits, demonstrates high specificity and sensitivity when detecting COX5B in human samples, making it suitable for Western blot applications.By targeting the COX5B protein, researchers can investigate its involvement in mitochondrial energy production and respiratory function.
Dysregulation of COX5B has been implicated in various diseases, including cancer and metabolic disorders, underscoring the importance of studying its mechanisms of action. The COX5B Polyclonal Antibody is a reliable tool for exploring these pathways and may offer insights into potential therapeutic targets for these conditions.
Product Name:
COX5B Rabbit Polyclonal Antibody
SKU:
CAB2640
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 32-129 of human COX5B (NP_001853.2).
Cytochrome C oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Vb of the human mitochondrial respiratory chain enzyme.
Purification Method:
Affinity purification
Gene ID:
1329
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using COX5B Rabbit pAb (CAB2640) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
