COX15 Rabbit Polyclonal Antibody (CAB14665)
- SKU:
- CAB14665
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | COX15 Rabbit Polyclonal Antibody |
SKU: | CAB14665 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human COX15 (NP_510870.1). |
Sequence: | YSHR MWGR LVGL VYIL PAAY FWRK GWLS RGMK GRVL ALCG LVCF QGLL GWYM VKSG LEEK SDSH DIPR VSQY RLAA HLGS ALVL YCAS LWTS LSLL LPPH K |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | MC4DN6; CEMCOX2; COX15 |
Positive Sample: | U-251MG,A-431,Jurkat,Mouse heart,Mouse kidney,Mouse lung,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion membrane, Multi-pass membrane protein. |
Calculated MW: | 46kDa |
Observed MW: | 60kDa |
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates two transcript variants diverging in the 3' region.
Purification Method: | Affinity purification |
Gene ID: | 1355 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |