The COX1 Polyclonal Antibody (CAB7531) is a valuable tool for researchers studying Cyclooxygenase 1 (COX1), an enzyme involved in the production of prostaglandins and thromboxane A2, important mediators of inflammation. This antibody is produced in rabbits and is highly reactive with human samples, making it an ideal choice for Western blot applications. By binding specifically to the COX1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it a versatile tool for studies in immunology, inflammation, and cancer research.COX1 is a key enzyme in the inflammatory response and is known to play a role in various diseases, including cancer, cardiovascular disease, and inflammatory conditions.
By studying the activity of COX1, researchers can gain valuable insights into the mechanisms of inflammation and potentially identify new therapeutic targets for the treatment of these diseases. The COX1 Polyclonal Antibody provides researchers with a reliable tool for investigating the role of COX1 in health and disease, offering new opportunities for advancing our understanding of inflammation and its impact on human health.
Product Name:
COX1 Rabbit Polyclonal Antibody
SKU:
CAB7531
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 415-514 of mouse COX1 (NP_904330.1).
Enables cytochrome-c oxidase activity. Predicted to be involved in electron transport coupled proton transport; mitochondrial electron transport, cytochrome c to oxygen; and response to oxidative stress. Located in mitochondrial inner membrane. Part of mitochondrial respiratory chain complex IV. Is expressed in several structures, including brown fat; heart; liver; metanephros; and skeletal muscle. Orthologous to human MT-CO1 (mitochondrially encoded cytochrome c oxidase I).
Purification Method:
Affinity purification
Gene ID:
17708
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from NIH/3T3 cells, using COX1 Rabbit pAb (CAB7531) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
