CoV Spike Bovine (CPAB0413)
- SKU:
- CPAB0413
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
system_update_alt Datasheet
CoV Spike Bovine (CPAB0413)
The COV-Spike Bovine Polyclonal Antibody (CPAB0413) is a crucial tool for researchers studying the spike protein of the novel coronavirus (SARS-CoV-2). This antibody, generated in bovine hosts, exhibits high sensitivity and specificity for detecting the spike protein in various sample types. Validated for use in applications such as ELISA and immunofluorescence, this antibody allows for the precise detection and quantification of the spike protein, aiding in the understanding of viral infection mechanisms and the development of diagnostic tools and therapies for COVID-19.
Its versatility and reliability make it an essential component in COVID-19 research and vaccine development efforts.
Product Name: | CoV Spike Bovine |
Product Sku: | CPAB0413 |
Size: | 50μg |
Host Species: | |
Immunogen: | The antibody was developed using purified bovine coronavirus(eptopoe not mapped). |
Clone: | |
Reactivity: | Viral |
Applications: | ELISA |
Purification Method: | |
Isotype: | |
Background: | SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies. It has recently been shown that SARS (severe acute respiratory syndrome) is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The glycosilated spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients. |
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