null

COTL1 Monoclonal Antibody [PAT1D6AT] (CPAB0607)

SKU:
CPAB0607
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT1D6AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

COTL1 Monoclonal Antibody [PAT1D6AT] (CPAB0607)

The COTL1 Polyclonal Antibody (CPAB0607) is a valuable tool for researchers studying COTL1, a protein involved in various cellular processes, including cytoskeleton organization and cell migration. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the COTL1 protein, this antibody enables accurate detection and analysis in a wide range of cell types, making it an ideal choice for studies in cell biology and cancer research.

COTL1, also known as Coactosin-like protein 1, plays a crucial role in regulating actin dynamics and promoting cell motility. Its involvement in these key cellular processes makes it a promising target for research into cancer metastasis, cell invasion, and cytoskeleton dynamics. By studying the function of COTL1, researchers can gain insights into the mechanisms underlying these processes and potentially uncover new therapeutic targets for cancer treatment.

Product Name:COTL1 Antibody
Product Sku:CPAB0607
Size:5μg
Host Species:Mouse
Immunogen:Anti-human COTL1 mAb, clone PAT1D6AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human COTL1 protein 1-142 amino acids purified from Ecoli.
Clone:PAT1D6AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:COTL1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:Coactosin-like protein (COTL1) is one of the numerous actin-binding proteins which regulate the actin cytoskeleton. COTL1 binds F-actin, it also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. COTL1 binds to F-actin in a calcium-independent way and has no direct effect on actin depolymerization.
Synonyms:Coactosin-like protein, COTL1, CLP, FLJ43657, MGC19733.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Related Products