The Coronin 1C Polyclonal Antibody (CAB4568) is a valuable tool for researchers studying Coronin 1C, a protein involved in cell motility and immune responses. This antibody, produced in rabbits, demonstrates high specificity for human samples and is validated for use in Western blot applications. By binding to Coronin 1C, this antibody allows for the detection and analysis of the protein in various cell types, making it ideal for investigations in immunology and cancer research.
Coronin 1C is known for its role in regulating actin dynamics and cellular movement, as well as its involvement in immune cell function. Its function in these processes makes it a compelling target for research into diseases like cancer, inflammatory disorders, and autoimmune conditions. Understanding the mechanisms by which Coronin 1C impacts cellular behavior and immune responses is crucial for advancing therapeutic approaches aimed at targeting these pathways.
Product Name:
CORO1C Rabbit Polyclonal Antibody
SKU:
CAB4568
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 375-474 of human CORO1C (NP_055140.1).
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Three transcript variants encoding two different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
23603
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of SW480 cells, using CORO1C antibody (CAB4568) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
