The Coro2A Polyclonal Antibody (CAB14469) is a valuable tool for researchers studying Coro2A, a protein involved in various cellular processes, including chromatin remodeling and gene regulation. This antibody, produced through immunization of rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the Coro2A protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in the fields of molecular biology and gene expression regulation.Coro2A, also known as Coronin-2A, is known to play a crucial role in cellular functions such as cell signaling, cytoskeleton organization, and protein trafficking.
Its involvement in these processes makes it a promising target for research focused on understanding cellular dynamics and function. By studying the activity of Coro2A, researchers may gain insights into various diseases such as cancer, neurodegenerative disorders, and autoimmune conditions, where dysregulation of cellular pathways is a key factor.Overall, the Coro2A Polyclonal Antibody (CAB14469) provides a valuable tool for researchers seeking to investigate the role of Coro2A in cellular processes and disease pathways. Its high specificity and reactivity make it a reliable choice for studying the function and regulation of Coro2A in a variety of research applications.
Product Name:
CORO2A Rabbit Polyclonal Antibody
SKU:
CAB14469
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 376-525 of human CORO2A (NP_003380.3).
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants.
Purification Method:
Affinity purification
Gene ID:
7464
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CORO2A Rabbit pAb (CAB14469) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
