The CORO1B Antibody (CAB14593) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples.Coro1B, also known as Coronin 1B, plays a crucial role in regulating the dynamics of the actin cytoskeleton, which is essential for cell motility and immune cell function. Dysregulation of Coro1B has been linked to various diseases, including cancer and autoimmune disorders, making it a promising target for therapeutic interventions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Rat samples.
Product Name:
CORO1B Antibody
SKU:
CAB14593
Size:
20μL, 100μL
Reactivity:
Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CORONIN-2, CORO1B
Positive Sample:
Rat kidney
Cellular Localization:
Cytoplasm, Cytoskeleton.
Calculated MW:
54kDa
Observed MW:
54kDa
Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility (Cai et al., 2005 [PubMed 16027158]).
Purification Method
Affinity purification
Gene ID
57175
RRID
AB_2761468
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat kidney, using CORO1B Rabbit pAb (CAB14593) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
